2-Bromo-2-methylpropionyl bromide → HCID 67302873, compound

HRID 888822Notes

Reaction equation

HRID 888822 reaction equation
[CH:1]1([NH:7][NH:8][C:9]([O:11][CH2:12][C:13]2[CH:18]=[CH:17][CH:16]=[CH:15][CH:14]=2)=[O:10])[CH2:6][CH2:5][CH2:4][CH2:3][CH2:2]1.[Br:19][C:20]([CH3:25])([CH3:24])[C:21](Br)=[O:22]>>[Br:19][C:20]([CH3:25])([CH3:24])[C:21]([N:7]([CH:1]1[CH2:2][CH2:3][CH2:4][CH2:5][CH2:6]1)[NH:8][C:9]([O:11][CH2:12][C:13]1[CH:14]=[CH:15][CH:16]=[CH:17][CH:18]=1)=[O:10])=[O:22]

Participants

3

Reactant 2

HCID 886852-Bromo-2-methylpropionyl bromideHCID 67302935HCID 67302935, compound

Product 1

HCID 67302873HCID 67302873, compound

Procedure

Benzyl 2-cyclohexylhydrazinecarboxylate and 2-bromoisobutyryl bromide were used for a similar reaction and treatment as Process 3 of Example 1, and benzyl 2-(2-bromoisobutyryl)-2-cyclohexylhydrazinecarboxylate was obtained as a white oil.

Sources & evidence

ORD record
ord-d190a0d80c45407889fd56c46fdb9dea
Source dataset
uspto-grants-2012_08
Patent number
US08252781B2

Reaction notes

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