2-Bromo-2-methylpropionyl bromide → HCID 67303026, compound

HRID 888828Notes

Reaction equation

HRID 888828 reaction equation
[CH:1]1([NH:9][NH:10][C:11]([O:13][CH2:14][C:15]2[CH:20]=[CH:19][CH:18]=[CH:17][CH:16]=2)=[O:12])[CH2:8][CH2:7][CH2:6][CH2:5][CH2:4][CH2:3][CH2:2]1.[Br:21][C:22]([CH3:27])([CH3:26])[C:23](Br)=[O:24]>>[Br:21][C:22]([CH3:27])([CH3:26])[C:23]([N:9]([CH:1]1[CH2:8][CH2:7][CH2:6][CH2:5][CH2:4][CH2:3][CH2:2]1)[NH:10][C:11]([O:13][CH2:14][C:15]1[CH:16]=[CH:17][CH:18]=[CH:19][CH:20]=1)=[O:12])=[O:24]

Participants

3

Reactant 2

HCID 886852-Bromo-2-methylpropionyl bromideHCID 67302845HCID 67302845, compound

Product 1

HCID 67303026HCID 67303026, compound

Procedure

Benzyl 2-cyclooctylhydrazinecarboxylate and 2-bromoisobutyryl bromide were used for a similar reaction and treatment as Process 3 of Example 1, and benzyl 2-(2-bromoisobutyryl)-2-cyclooctylhydrazinecarboxylate was obtained as a pale yellow oil.

Sources & evidence

ORD record
ord-665a09d1609246f393116361cba75e47
Source dataset
uspto-grants-2012_08
Patent number
US08252781B2

Reaction notes

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