2-Bromo-2-methylpropionyl bromide → HCID 67303150, compound

HRID 888847Notes

Reaction equation

HRID 888847 reaction equation
[CH3:1][O:2][C:3]([C:5]12[CH2:14][CH:9]3[CH2:10][CH:11]([CH2:13][CH:7]([CH:8]3[NH:15][NH:16][C:17]([O:19][CH2:20][C:21]3[CH:26]=[CH:25][CH:24]=[CH:23][CH:22]=3)=[O:18])[CH2:6]1)[CH2:12]2)=[O:4].[Br:27][C:28]([CH3:33])([CH3:32])[C:29](Br)=[O:30]>>[Br:27][C:28]([CH3:33])([CH3:32])[C:29]([N:15]([CH:8]1[CH:9]2[CH2:10][CH:11]3[CH2:12][C:5]([C:3]([O:2][CH3:1])=[O:4])([CH2:6][CH:7]1[CH2:13]3)[CH2:14]2)[NH:16][C:17]([O:19][CH2:20][C:21]1[CH:22]=[CH:23][CH:24]=[CH:25][CH:26]=1)=[O:18])=[O:30]

Participants

3

Reactant 2

HCID 886852-Bromo-2-methylpropionyl bromideHCID 67303256HCID 67303256, compound

Product 1

HCID 67303150HCID 67303150, compound

Procedure

Benzyl 2-(5-methoxycarbonyladamantan-2-yl)hydrazinecarboxylate and 2-bromoisobutyrylbromide were used for a similar reaction and treatment as Process 3 of Example 1, and benzyl 2-(2-bromoisobutyryl)-2-(5-methoxycarbonyladamantan-2-yl)hydrazinecarboxylate was obtained as a colorless oil.

Sources & evidence

ORD record
ord-e6a82c68f5304b91ab2295bd17d95b37
Source dataset
uspto-grants-2012_08
Patent number
US08252781B2

Reaction notes

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