2-Bromo-2-methylpropionyl bromide → HCID 67303351, compound

HRID 888880Notes

Reaction equation

HRID 888880 reaction equation
[CH:1]12[CH2:10][CH:5]3[CH2:6][CH:7]([CH2:9][CH:3]([CH2:4]3)[CH:2]1[NH:11][NH:12][C:13]1[CH:18]=[CH:17][CH:16]=[CH:15][C:14]=1[N+:19]([O-:21])=[O:20])[CH2:8]2.[Br:22][C:23]([CH3:28])([CH3:27])[C:24](Br)=[O:25]>>[Br:22][C:23]([CH3:28])([CH3:27])[C:24]([N:11]([CH:2]1[CH:3]2[CH2:9][CH:7]3[CH2:6][CH:5]([CH2:10][CH:1]1[CH2:8]3)[CH2:4]2)[NH:12][C:13]1[CH:18]=[CH:17][CH:16]=[CH:15][C:14]=1[N+:19]([O-:21])=[O:20])=[O:25]

Participants

3

Reactant 2

HCID 886852-Bromo-2-methylpropionyl bromideHCID 67303093HCID 67303093, compound

Product 1

HCID 67303351HCID 67303351, compound

Procedure

1-(Adamantan-2-yl)-2-(2-nitrophenyl)hydrazine prepared in Processes 1 and 2 in Example 180 and 2-bromoisobutyryl bromide were used for a similar reaction and treatment as Process 3 of Example 1, and 2-bromo-N-(adamantan-2-yl)-2-methyl-N′-(2-nitrophenyl)propane hydrazide was obtained as a yellow oil.

Workup

  1. customwere used for a similar reaction and treatment as Process 3 of Example 1

Sources & evidence

ORD record
ord-c9ad12df02394ed0b814ca4c08d7a63a
Source dataset
uspto-grants-2012_08
Patent number
US08252781B2

Reaction notes

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