反应详情

温度

85 °C

A mixture of 1,3-dipropyl-8-{4-[3-(4-trifluoromethoxy-phenyl)-prop-2-ynyloxy]-phenyl}-7-(2-trimethylsilanyl-ethoxymethyl)-3,7-dihydro-purine-2,6-dione (0.053 g, 0.055 mmol), 2N HCl (2 ml), ethanol (2 ml) was heated at 85° C. for 2 hours. The mixture was cooled and the solvent was evaporated. The residue was washed with n-pentane to obtain 1,3-dipropyl-8-{4-[3-(4-trifluoromethoxy-phenyl)-prop-2-ynyloxy]-phenyl}-3,7-dihydro-purine-2,6-dione (0.038 g, 88%).

1. temperatureThe mixture was cooled
2. customthe solvent was evaporated
3. washThe residue was washed with n-pentane