Hydrochloric Acid → HCID 57988765, compound

Participants

Reaction Conditions

Reaction Steps

A mixture of 1,3-dipropyl-8-{1-[2-(3-trifluoromethyl-phenyl)-cyclopropylmethyl]-1H-pyrazol-4-yl}-7-(2-trimethylsilanyl-ethoxymethyl)-3,7-dihydro-purine-2,6-dione (0.55 g, 0.087 mmol), 2 N HCl (2 ml), ethanol (3 ml) were heated at 85° C. for 3 hours. The mixture was cooled to 10-15° C. and solid material was separated. It was filtered off and washed with water (1 ml), diethyl ether (1 ml) to obtain the title compound (0.016 g, 37

Provenance & Evidence