3,5-Dimethylpyrazole → HCID 131729911, compound

Participants

Reaction Conditions

Reaction Steps

(2-Chloro-quinazolin-4-yl)-propylamine (450 mg, 2.03 mmol) was dissolved in acetonitrile (7.5 mL) and 3,5-dimethylpyrazole (215 mg, 2.23 mmol) was added. The mixture was heated in a microwave oven at 170° C. for 20 minutes. Filtration gave [2-(3,5-dimethylpyrazol-1-yl)-quinazolin-4-yl]-propylamine, hydrochloride (290 mg, 51%) as a pale red crystalline compound. Mp. 208° C.

Provenance & Evidence