3,5-Dimethylpyrazole → HCID 131729923, compound

HRID 889092Notes

Reaction equation

HRID 889092 reaction equation
[Cl:1][C:2]1[N:11]=[C:10](Cl)[C:9]2[C:4](=[CH:5][CH:6]=[CH:7][CH:8]=2)[N:3]=1.[F:13][C:14]1[CH:15]=[C:16]([CH:19]=[CH:20][C:21]=1[F:22])[CH2:17][NH2:18].[CH3:23][C:24]1[CH:28]=[C:27]([CH3:29])[NH:26][N:25]=1>>[ClH:1].[F:13][C:14]1[CH:15]=[C:16]([CH:19]=[CH:20][C:21]=1[F:22])[CH2:17][NH:18][C:10]1[C:9]2[C:4](=[CH:5][CH:6]=[CH:7][CH:8]=2)[N:3]=[C:2]([N:25]2[C:24]([CH3:23])=[CH:28][C:27]([CH3:29])=[N:26]2)[N:11]=1

Participants

4

Reactant 3

HCID 62103,5-DimethylpyrazoleHCID 1235723,4-DifluorobenzylamineHCID 2528862,4-Dichloroquinazoline

Product 1

HCID 131729923HCID 131729923, compound

Procedure

Was prepared according to Method A from 2,4-dichloroquinazoline, 3,4-difluorobenzylamine and 3,5-dimethylpyrazole. Mp. 165° C.

Workup

  1. customWas prepared

Sources & evidence

ORD record
ord-8974d434d8444247bd3e3a476264fc0d
Source dataset
uspto-grants-2012_08
Patent number
US08252806B2

Reaction notes

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