HRID889251

反应详情

EQUATION

反应方程式

REACTANTS

反应物

结构：O=C1CN(c2c(F)cc(I)cc2OCc2ccccc2)S(=O)(=O)N1COCc1ccccc1

HCID68429310

未命名化合物

HCID68429608

未命名化合物

PRODUCTS

生成物

结构：Cc1ccc(Cc2cc(F)c(N3CC(=O)N(COCc4ccccc4)S3(=O)=O)c(OCc3ccccc3)c2)c(NC(=O)OC(C)(C)C)c1

HCID68429549

未命名化合物

PROCEDURE

实验过程

The title compound is prepared analogously to Example 1, Step M, with (2-iodomethyl-5-methylphenyl)-carbamic acid tert-butyl ester and 5-(2-benzyloxy-6-fluoro-4-iodophenyl)-2-benzyloxymethyl-1,1-dioxo-1,2,5-thiadiazolidin-3-one.

来源与证据

来源类型: Open Reaction Database
ORD 记录: ord-9f4c1800279041d79fb03d26307d09e7
来源数据集: uspto-grants-2012_08
DOI: 10.6084/m9.figshare.5104873.v1
专利: US08252820B2
来源说明: uspto-grants-2012_08

反应 SMILES

[C:1]([O:5][C:6](=[O:17])[NH:7][C:8]1[CH:13]=[C:12]([CH3:14])[CH:11]=[CH:10][C:9]=1[CH2:15]I)([CH3:4])([CH3:3])[CH3:2].[CH2:18]([O:25][C:26]1[CH:31]=[C:30](I)[CH:29]=[C:28]([F:33])[C:27]=1[N:34]1[S:38](=[O:40])(=[O:39])[N:37]([CH2:41][O:42][CH2:43][C:44]2[CH:49]=[CH:48][CH:47]=[CH:46][CH:45]=2)[C:36](=[O:50])[CH2:35]1)[C:19]1[CH:24]=[CH:23][CH:22]=[CH:21][CH:20]=1>>[C:1]([O:5][C:6](=[O:17])[NH:7][C:8]1[CH:13]=[C:12]([CH3:14])[CH:11]=[CH:10][C:9]=1[CH2:15][C:30]1[CH:29]=[C:28]([F:33])[C:27]([N:34]2[CH2:35][C:36](=[O:50])[N:37]([CH2:41][O:42][CH2:43][C:44]3[CH:49]=[CH:48][CH:47]=[CH:46][CH:45]=3)[S:38]2(=[O:40])=[O:39])=[C:26]([O:25][CH2:18][C:19]2[CH:24]=[CH:23][CH:22]=[CH:21][CH:20]=2)[CH:31]=1)([CH3:4])([CH3:3])[CH3:2]