HuagongsheHuagongshe Chemistry Print Report · For research reference only
5-(2-Benzyloxy-6-fluoro-4-iodophenyl)-2-benzyloxymethyl-1,1-dioxo-1,2,5-thiadiazolidin-3-one → {2-[3-Benzyloxy-4-(5-benzyloxymethyl-1,1,4-trioxo-1,2,5-thiadiazolidin-2-yl)-5-fluorobenzyl]-5-methylphenyl}-carbamic acid tert-butyl ester
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 5-(2-Benzyloxy-6-fluoro-4-iodophenyl)-2-benzyloxymethyl-1,1-dioxo-1,2,5-thiadiazolidin-3-one | HCID 68429310 | — |
| Reactant | (2-Iodomethyl-5-methylphenyl)-carbamic acid tert-butyl ester | HCID 68429608 | — |
| Product | {2-[3-Benzyloxy-4-(5-benzyloxymethyl-1,1,4-trioxo-1,2,5-thiadiazolidin-2-yl)-5-fluorobenzyl]-5-methylphenyl}-carbamic acid tert-butyl ester | HCID 68429549 | — |
Reaction Steps
The title compound is prepared analogously to Example 1, Step M, with (2-iodomethyl-5-methylphenyl)-carbamic acid tert-butyl ester and 5-(2-benzyloxy-6-fluoro-4-iodophenyl)-2-benzyloxymethyl-1,1-dioxo-1,2,5-thiadiazolidin-3-one.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08252820B2 |
| Source dataset | uspto-grants-2012_08 |
| ORD ID | ord-9f4c1800279041d79fb03d26307d09e7 |
| Source note | uspto-grants-2012_08 |