Hydrazine → HCID 178515623, compound

Participants

Reaction Steps

5-(4-Fluoro-phenyl)-1H-pyrazol-3-ol (7.67 g, 84%) was prepared as a white solid from 3-(4-Fluoro-phenyl)-3-oxo-propionic acid methyl ester (10.0 g, 51.0 mmol) and hydrazine (4.76 mL, 153 mmol) by a procedure analogous to Example 22. C9H7FN2O: 1H NMR (d6-DMSO): δ 7.66 (dd, 2H, JCH—CF=11.7 Hz, JCH—CH=8.7 Hz), 7.21 (d, 2H, J=8.7 Hz), 5.83 (s, 1H) ppm.

Provenance & Evidence