Pyridine → 4,5-dichloro-N-[3,3,3-trifluoro-1-(hydroxymethyl)-2-(trifluoromethyl)propyl]thiophene-2-sulfonamide
Reaction equation
[CH2:31]1[O:32][CH2:33][CH2:34][CH2:35]1.[Cl:20][c:21]1[cH:22][c:23]([S:27](=[O:28])(=[O:29])[Cl:30])[s:24][c:25]1[Cl:26].[F:1][C:2]([CH:3]([CH:4]([CH2:5][OH:6])[NH2:7])[C:8]([F:9])([F:10])[F:11])([F:12])[F:13].[cH:14]1[cH:15][cH:16][n:17][cH:18][cH:19]1>>[F:1][C:2]([CH:3]([CH:4]([CH2:5][OH:6])[NH:7][S:27]([c:23]1[cH:22][c:21]([Cl:20])[c:25]([Cl:26])[s:24]1)(=[O:28])=[O:29])[C:8]([F:9])([F:10])[F:11])([F:12])[F:13]Participants
5
Reactant 4
Product 1
Sources & evidence
- ORD record
- ord-d21668e035de46d7ba1b499dbc7fdd49
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (2/10)
Reaction notes
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