Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Acrylonitrile | HCID 7855 | — |
| Reactant | 7-chloro-2-methyl-1H-indole | HCID 11816062 | — |
| Solvent | 1,4-Dioxane | HCID 31275 | — |
| Product | HCID 22250584 | HCID 22250584 | — |
Reaction Steps
20 g of 7-chloro-2-methyl-1H-indole are mixed in 100 ml of dioxane with 3 g of triton B, 3 g of acrylonitrile are slowly added, 250 ml of dioxane are added again and then the mixture is heated at 60° C. for 2 hours. The medium is evaporated and then the residue is taken up in AcOEt. The precipitate formed being removed, the product obtained is used as is in the following stage.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| Patent number | US06995184B2 |
|---|
| Source dataset | uspto-grants-2006_02 |
|---|
| ORD ID | ord-ba29b17d0fe24ef58b35fa9cc419cc88 |
|---|
| Source note | uspto-grants-2006_02 |
|---|
