HuagongsheHuagongshe Chemistry Print Report · For research reference only
Ethyl bromoacetate → ethyl (4-{[tert-butyl(dimethyl)silyl]oxy}-1H-indol-1-yl)acetate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Ethyl bromoacetate | HCID 7748 | — |
| Reactant | Cesium carbonate | HCID 10796 | — |
| Reactant | 4-(t-Butyldimethylsilyloxy)indole | HCID 11593976 | — |
| Product | ethyl (4-{[tert-butyl(dimethyl)silyl]oxy}-1H-indol-1-yl)acetate | HCID 68822793 | — |
Reaction Steps
In analogy to the procedure described in example 6 a], 4-(tert-butyl-dimethyl-silanyloxy)-1H-indole (EP 206225 A2) was reacted with bromo-acetic acid ethyl ester in the presence of cesium carbonate to obtain the title compound as yellow oil.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06995263B2 |
| Source dataset | uspto-grants-2006_02 |
| ORD ID | ord-a58b05aae28e4e858b89e11fa3033b88 |
| Source note | uspto-grants-2006_02 |