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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 890459Generated: October 26, 2026

1-Butanaminium, N,N,N-tributyl-, fluoride, hydrate → ethyl (4-hydroxy-1H-indol-1-yl)acetate

https://huagongshe.com/reaction/890459

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1-Butanaminium, N,N,N-tributyl-, fluoride, hydrateHCID 16211673—
ReactantHCID 68822793HCID 68822793—
Productethyl (4-hydroxy-1H-indol-1-yl)acetateHCID 68822476—

Reaction Steps

In analogy to the procedure described in example 6 b], [4-(tert-butyl-dimethyl-silanyloxy)-indol-1-yl]-acetic acid ethyl ester was treated with tetrabutylammonium fluoride hydrate to obtain (4-hydroxy-indol-1-yl)-acetic acid ethyl ester as yellow oil.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06995263B2
Source datasetuspto-grants-2006_02
ORD IDord-03ae51af8cf842be9be88ba4ed67756d
Source noteuspto-grants-2006_02