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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 890493Generated: November 2, 2026

Methanol → [4-Cyclopropyl-2-(4-trifluoromethyl-phenyl)-pyrimidin-5-yl]-acetic acid methyl ester

https://huagongshe.com/reaction/890493

Reaction equation

Participants

RoleNameHCIDCharge
ReactantMethanolHCID 887—
Reactant[4-Cyclopropyl-2-(4-trifluoromethyl-phenyl)-pyrimidin-5-yl]-acetic acidHCID 21935630—
Product[4-Cyclopropyl-2-(4-trifluoromethyl-phenyl)-pyrimidin-5-yl]-acetic acid methyl esterHCID 69036962—

Reaction Steps

In analogy to the procedure described in example 8 d], [4-cyclopropyl-2-(4-trifluoromethyl-phenyl)-pyrimidin-5-yl]-acetic acid was esterified with methanol to give the title compound as yellow solid.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06995263B2
Source datasetuspto-grants-2006_02
ORD IDord-de7ca925457543c4921437f2359d96a0
Source noteuspto-grants-2006_02