Hydrochloric Acid → HCID 131725272, compound

Participants

Reaction Steps

2-(3,5-Difluoro-benzyloxy)-4-piperazin-1-yl-pyrimidine (1-A) (27.5 mg, 0.09 mmol) was dissolved in 1 mL of dichloromethane and treated with 1M hydrogen chloride in ether (89.8 μL, 0.09 mmol) and shaken for one minute. The reaction was then concentrated under a stream of nitrogen to give 30.8 mg of a yellow solid as the title compound (1-B).

Provenance & Evidence