HuagongsheHuagongshe Chemistry Print Report · For research reference only
(6-Chloropyridin-2-yl)methanol → 4-[2-(6-Chloro-pyridin-2-ylmethoxy)-pyrimidin-4-yl]-piperazine-1-carboxylic Acid Tert-Butyl Ester
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | (6-Chloropyridin-2-yl)methanol | HCID 182139 | — |
| Reactant | Tert-butyl 4-(2-chloropyrimidin-4-yl)piperazine-1-carboxylate | HCID 11197306 | — |
| Product | 4-[2-(6-Chloro-pyridin-2-ylmethoxy)-pyrimidin-4-yl]-piperazine-1-carboxylic Acid Tert-Butyl Ester | HCID 86588364 | — |
Reaction Steps
The title compound (I-5b) was prepared from (6-chloro-pyridin-2-yl)-methanol (I-5a) and 4-(2-chloro-pyrimidin-4-yl)-piperazine-1-carboxylic acid tert-butyl ester (I-1 a) according to a procedure analogous to that described in Example 1.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06995159B2 |
| Source dataset | uspto-grants-2006_02 |
| ORD ID | ord-8a2202714c4245c495c53c783c56b026 |
| Source note | uspto-grants-2006_02 |