Water → 4,5-Diphenyl-4-oxazolin-2-one

HRID 890869ノート

反応式

HRID 890869 の反応式
[C:1]1([C:7]([CH:9]([C:11]2[CH:16]=[CH:15][CH:14]=[CH:13][CH:12]=2)[OH:10])=O)[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1.[NH2:17][C:18](OCC)=[O:19].O>CC(C)=O>[C:1]1([C:7]2[NH:17][C:18](=[O:19])[O:10][C:9]=2[C:11]2[CH:16]=[CH:15][CH:14]=[CH:13][CH:12]=2)[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1

参加物

5

反応物 3

HCID 962WaterHCID 5641Carbamic acid, ethyl esterHCID 8400Benzoin

生成物 1

HCID 1512454,5-Diphenyl-4-oxazolin-2-one

試薬・触媒・溶媒 1

HCID 180Acetone溶媒

実験手順

Benzoin (31.8 g, 0.15 mol) and urethane (42.79 g, 0.45 mol) were heated to reflux for 3.0 hours. The hot mixture was poured into water (150 mL). Acetone (150 mL) was added and heat was applied until the mixture dissolved. The solution was cooled and filtered, producing a white solid which was used in the next step without further purification.

後処理

  1. temperatureto reflux for 3.0 hours
  2. temperatureheat
  3. dissolutiondissolved
  4. temperatureThe solution was cooled
  5. filtrationfiltered
  6. customproducing a white solid which
  7. customwas used in the next step without further purification

出典と根拠

ORDレコード
ord-47f774078ceb4618a0731b11914bd4c0
出典データセット
uspto-grants-2006_02
特許番号
US06998415B2

反応ノート

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