4-ethoxybenzenesulfonamide → HCID 22244532, compound

HRID 891111Notes

Reaction equation

[CH3:1][C:2]1[C:6]([C:7]2[CH:12]=[CH:11][CH:10]=[CH:9][CH:8]=2)=[C:5]([CH3:13])[N:4]([C:14]2[CH:19]=[CH:18][C:17]([CH2:20][CH2:21][NH:22][C:23](=[O:31])OC3C=CC=CC=3)=[CH:16][CH:15]=2)[N:3]=1.[CH2:32]([O:34][C:35]1[CH:40]=[CH:39][C:38]([S:41]([NH2:44])(=[O:43])=[O:42])=[CH:37][CH:36]=1)[CH3:33]>>[CH3:1][C:2]1[C:6]([C:7]2[CH:12]=[CH:11][CH:10]=[CH:9][CH:8]=2)=[C:5]([CH3:13])[N:4]([C:14]2[CH:15]=[CH:16][C:17]([CH2:20][CH2:21][NH:22][C:23]([NH:44][S:41]([C:38]3[CH:37]=[CH:36][C:35]([O:34][CH2:32][CH3:33])=[CH:40][CH:39]=3)(=[O:42])=[O:43])=[O:31])=[CH:18][CH:19]=2)[N:3]=1

Participants

Reactant 2

HCID 37240054-ethoxybenzenesulfonamide

HCID 22244550Phenyl 2-[4-(3,5-dimethyl-4-phenyl-1H-pyrazol-1-yl)phenyl]ethylcarbamate

Product 1

HCID 22244532HCID 22244532, compound

Procedure

The title compound was prepared according to the procedure described in step 1 of Example 42 from phenyl 2-[4-(3,5-dimethyl-4-phenyl-1H-pyrazol-1-yl)phenyl]ethylcarbamate (step 1 of Example 22) and 4-ethoxybenzenesulfonamide [Chem. Ber., 1982, 25, 1838]: 1H-NMR (CDCl3) δ 7.74 (2H, d, J=8.9 Hz), 7.47-7.24 (9H, m), 6.95-6.92 (21H, in), 6.40 (1H, br.s), 4.07 (2H, q, J=7.1 Hz), 3.53-3.46 (2H, m), 2.86 (2H, t, J=6.8 Hz), 2.33 (3H, s), 2.26 (3H, s), 1.42 (3H, t, J=7.1 Hz).

Sources & evidence

ORD record: ord-37f751d3f8bd413188cbacc1386a2df8
Source dataset: uspto-grants-2006_02
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US07001917B2

Reaction notes

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