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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 891115Generated: October 31, 2026

2,6-Difluorobenzenesulfonamide → N-[({2-[4-(3,5-Dimethyl-4-phenyl-1H-pyrazol-1-yl)phenyl]ethyl}amino)carbonyl]-2,6-difluorobenzenesulfonamide

https://huagongshe.com/reaction/891115

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2,6-DifluorobenzenesulfonamideHCID 446274—
ReactantPhenyl 2-[4-(3,5-dimethyl-4-phenyl-1H-pyrazol-1-yl)phenyl]ethylcarbamateHCID 22244550—
ProductN-[({2-[4-(3,5-Dimethyl-4-phenyl-1H-pyrazol-1-yl)phenyl]ethyl}amino)carbonyl]-2,6-difluorobenzenesulfonamideHCID 22244553—

Reaction Steps

The title compound was prepared according to the procedure described in step 1 of Example 42 from phenyl 2-[4-(3,5-dimethyl-4-phenyl-1H-pyrazol-1-yl)phenyl]ethylcarbamate (step 1 of Example 22) and 2,6-difluorobenzenesulfonamide: 1H-NMR (CDCl3) δ 7.44-7.19 (10H, m), 6.93 (2H, t, J=9.0 Hz), 6.52 (1H, br.s), 3.39-3.37 (2H, m), 2.79-2.74 (2H, m), 2.29 (3H, s), 2.20 (3H, s).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07001917B2
Source datasetuspto-grants-2006_02
ORD IDord-b1ac2090453d4defb9ccec4b2d0b16ed
Source noteuspto-grants-2006_02