HuagongsheHuagongshe Chemistry Print Report · For research reference only
Phenylboronic Acid → 2-{4-[5-Methyl-4-phenyl-3-(trifluoromethyl)-1H-pyrazol-1-yl]phenyl}ethanol
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Phenylboronic Acid | HCID 66827 | — |
| Reactant | 2-{4-[4-Bromo-5-methyl-3-(trifluoromethyl)-1H-pyrazol-1-yl]phenyl}ethanol | HCID 22244684 | — |
| Product | 2-{4-[5-Methyl-4-phenyl-3-(trifluoromethyl)-1H-pyrazol-1-yl]phenyl}ethanol | HCID 22244638 | — |
Reaction Steps
The title compound was prepared according to the procedure described in step 1 of Example 12 from 2-{4-[4-bromo-5-methyl-3-(trifluoromethyl)-1H-pyrazol-1-yl]phenyl}ethanol (step 2) and phenylboronic acid: MS (ESI) m/z 346 [M+H]+, 1H-NMR (CDCl3) δ 7.44-7.32 (9H, m), 3.89-3.83 (2H, m), 2.94-2.89 (2H, m), 2.33 (3H, s), 2:32 (3H, s)
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07001917B2 |
| Source dataset | uspto-grants-2006_02 |
| ORD ID | ord-0d1de417f4e346d3b168ffaed88449bf |
| Source note | uspto-grants-2006_02 |