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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 891119Generated: October 30, 2026

Phenylboronic Acid → 2-{4-[5-Methyl-4-phenyl-3-(trifluoromethyl)-1H-pyrazol-1-yl]phenyl}ethanol

https://huagongshe.com/reaction/891119

Reaction equation

Participants

RoleNameHCIDCharge
ReactantPhenylboronic AcidHCID 66827—
Reactant2-{4-[4-Bromo-5-methyl-3-(trifluoromethyl)-1H-pyrazol-1-yl]phenyl}ethanolHCID 22244684—
Product2-{4-[5-Methyl-4-phenyl-3-(trifluoromethyl)-1H-pyrazol-1-yl]phenyl}ethanolHCID 22244638—

Reaction Steps

The title compound was prepared according to the procedure described in step 1 of Example 12 from 2-{4-[4-bromo-5-methyl-3-(trifluoromethyl)-1H-pyrazol-1-yl]phenyl}ethanol (step 2) and phenylboronic acid: MS (ESI) m/z 346 [M+H]+, 1H-NMR (CDCl3) δ 7.44-7.32 (9H, m), 3.89-3.83 (2H, m), 2.94-2.89 (2H, m), 2.33 (3H, s), 2:32 (3H, s)

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07001917B2
Source datasetuspto-grants-2006_02
ORD IDord-0d1de417f4e346d3b168ffaed88449bf
Source noteuspto-grants-2006_02