HRID891123

反应详情

EQUATION

反应方程式

REACTANTS

反应物

HCID13668250

3-Sulfamoylbenzamide

C7H8N2O3S

结构：Cc1nn(-c2ccc(CCNC(=O)Oc3ccccc3)cc2)c(C)c1-c1ccccc1

HCID22244550

未命名化合物

PRODUCTS

生成物

结构：Cc1nn(-c2ccc(CCNC(=O)NS(=O)(=O)c3cccc(C(N)=O)c3)cc2)c(C)c1-c1ccccc1

HCID22244702

未命名化合物

PROCEDURE

实验过程

The title compound was prepared according to the procedure described in step 1 of Example 42 from phenyl 2-[4-(3,5-dimethyl-4-phenyl-1H-pyrazol-1-yl)phenyl]ethylcarbamate (step 1 of Example 22) and 3-(aminosulfonyl)benzamide: 1H-NMR (CDCl3) δ 8.47 (1H, s), 8.01 (2H, d, J=8.9 Hz), 7.60-7.11 (10H, m), 6.70 (1H, br.s), 6.30 (1H, br.s), 3.38-3.35 (2H, m), 2.77-2.71 (2H, m), 2.29 (3H, s), 2.17 (3H, s).

来源与证据

来源类型: Open Reaction Database
ORD 记录: ord-8ddaa57abf7b4c62b1d74e21b6d9491c
来源数据集: uspto-grants-2006_02
DOI: 10.6084/m9.figshare.5104873.v1
专利: US07001917B2
来源说明: uspto-grants-2006_02

反应 SMILES

[CH3:1][C:2]1[C:6]([C:7]2[CH:12]=[CH:11][CH:10]=[CH:9][CH:8]=2)=[C:5]([CH3:13])[N:4]([C:14]2[CH:19]=[CH:18][C:17]([CH2:20][CH2:21][NH:22][C:23](=[O:31])OC3C=CC=CC=3)=[CH:16][CH:15]=2)[N:3]=1.[NH2:32][S:33]([C:36]1[CH:37]=[C:38]([CH:42]=[CH:43][CH:44]=1)[C:39]([NH2:41])=[O:40])(=[O:35])=[O:34]>>[CH3:1][C:2]1[C:6]([C:7]2[CH:12]=[CH:11][CH:10]=[CH:9][CH:8]=2)=[C:5]([CH3:13])[N:4]([C:14]2[CH:15]=[CH:16][C:17]([CH2:20][CH2:21][NH:22][C:23]([NH:32][S:33]([C:36]3[CH:37]=[C:38]([CH:42]=[CH:43][CH:44]=3)[C:39]([NH2:41])=[O:40])(=[O:34])=[O:35])=[O:31])=[CH:18][CH:19]=2)[N:3]=1