3-Cyanophenylboronic acid → HCID 22244681, compound

HRID 891128Notes

Reaction equation

HRID 891128 reaction equation
I[C:2]1[C:3]([CH3:17])=[N:4][N:5]([C:8]2[CH:13]=[CH:12][C:11]([CH2:14][CH2:15][OH:16])=[CH:10][CH:9]=2)[C:6]=1[CH3:7].[C:18]([C:20]1[CH:21]=[C:22](B(O)O)[CH:23]=[CH:24][CH:25]=1)#[N:19]>>[OH:16][CH2:15][CH2:14][C:11]1[CH:12]=[CH:13][C:8]([N:5]2[C:6]([CH3:7])=[C:2]([C:24]3[CH:25]=[C:20]([CH:21]=[CH:22][CH:23]=3)[C:18]#[N:19])[C:3]([CH3:17])=[N:4]2)=[CH:9][CH:10]=1

Participants

3

Reactant 2

HCID 27343253-Cyanophenylboronic acidHCID 222445592-[4-(4-Iodo-3,5-dimethyl-1H-pyrazol-1-yl)phenyl]ethanol

Product 1

HCID 22244681HCID 22244681, compound

Procedure

The title compound was prepared according to the procedure described in step 1 of Example 12 from 2-[4-(4-iodo-3,5-dimethyl-1H-pyrazol-1-yl)phenyl]ethanol (step 2 of Example 11) and 3-cyanobenzeneboronic acid: MS (EI) m/z 317 [M]+, 1H-NMR (CDCl3) δ 7.63-7.34 (8H, m), 3.92 (2H, t, J=6.6 Hz), 2.94 (2H, t, J=6.6 Hz), 2.32 (3H, s), 2.29 (3H, s).

Sources & evidence

ORD record
ord-db31b655170a4a4eb5ae14ef5e9ed8cf
Source dataset
uspto-grants-2006_02
Patent number
US07001917B2

Reaction notes

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