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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 891142Generated: October 26, 2026

4-(Methanesulfonyl)benzene-1-sulfonamide → N-[({2-[4-(3,5-dimethyl-4-phenyl-1H-pyrazol-1-yl)phenyl]ethyl}amino) carbonyl]-4-(methylsulfonyl)benzenesulfonamide

https://huagongshe.com/reaction/891142

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-(Methanesulfonyl)benzene-1-sulfonamideHCID 120313—
ReactantPhenyl 2-[4-(3,5-dimethyl-4-phenyl-1H-pyrazol-1-yl)phenyl]ethylcarbamateHCID 22244550—
ProductN-[({2-[4-(3,5-dimethyl-4-phenyl-1H-pyrazol-1-yl)phenyl]ethyl}amino) carbonyl]-4-(methylsulfonyl)benzenesulfonamideHCID 22244530—

Reaction Steps

The title compound was prepared according to the procedure described in step 2 of Example 22 from phenyl 2-[4-(3,5-dimethyl-4-phenyl-1H-pyrazol-1-yl)phenyl]ethylcarbamate (step 1 of Example 22) and 4-(methylsulfonyl)benzenesulfonamide: 1H-NMR (CDCl3) δ 8.16-8.08 (4H, m), 7.47-7.20 (9H, m), 6.04 (1H, br.s), 3.46-3.41 (2H, m), 3.10 (3H, s), 2.87-2.82 (2H, m), 2.33 (3H, s), 2.22 (3H, s).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07001917B2
Source datasetuspto-grants-2006_02
ORD IDord-0f948a38073e4e1ca1352b2b8ebf8591
Source noteuspto-grants-2006_02