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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 891148Generated: October 30, 2026

pyridine-3-sulfonamide → N-{[(2-{4-[5-phenyl-3-(trifluoromethyl)-1H-pyrazol-1-yl]phenyl}ethyl)amino]carbonyl}pyridine-3-sulfonamide

https://huagongshe.com/reaction/891148

Reaction equation

Participants

RoleNameHCIDCharge
Reactantpyridine-3-sulfonamideHCID 232710—
ReactantHCID 22244661HCID 22244661—
ProductN-{[(2-{4-[5-phenyl-3-(trifluoromethyl)-1H-pyrazol-1-yl]phenyl}ethyl)amino]carbonyl}pyridine-3-sulfonamideHCID 22244518—

Reaction Steps

The title compound was prepared according to the procedure described in step 1 of Example 0.42 from phenyl 2-{4-[5-phenyl-3-(trifluoromethyl)-1H-pyrazol-1-yl]phenyl}ethylcarbamate (step 4) and pyridine-3-sulfonamide: 1H-NMR (CDCl3) δ 9.04 (1H, d, J=2.0 Hz), 8.78 (1H, d, J=3.7 Hz), 8.08-8.04 (1H, m), 7.48-7.44 (1H, m), 7.34-7.10 (9H, m), 6.76 (1H, s), 6.28 (1H, br.s), 3.48-3.42 (2H, m), 2.83-2.78 (2H, m).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07001917B2
Source datasetuspto-grants-2006_02
ORD IDord-9323689b780b4c2181a430f09c9f4220
Source noteuspto-grants-2006_02