反应详情

To a stirred solution of n-butyllithium (15.0 mL, 1.6 M in hexane solution, 24.0 mol) in dry ether (160 mL), a solution of 3,4,5-trimethoxyphenylbromide (2.97 g, 12.0 mol) in ether (40 mL) was added under dry nitrogen at −78° C. The solution was stirred for 1 h in order to form 3,4,5-trimethoxyphenyllithum.