HuagongsheHuagongshe Chemistry Print Report · For research reference only
5-Bromo-1,2,3-trimethoxybenzene → HCID 178418846, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 5-Bromo-1,2,3-trimethoxybenzene | HCID 75885 | — |
| Reactant | Butyllithium | HCID 178418339 | — |
| Solvent | Diethyl Ether | HCID 3283 | — |
| Product | HCID 178418846 | HCID 178418846 | — |
Reaction Steps
To a stirred solution of n-butyllithium (15.0 mL, 1.6 M in hexane solution, 24.0 mol) in dry ether (160 mL), a solution of 3,4,5-trimethoxyphenylbromide (2.97 g, 12.0 mol) in ether (40 mL) was added under dry nitrogen at −78° C. The solution was stirred for 1 h in order to form 3,4,5-trimethoxyphenyllithum.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07001926B2 |
| Source dataset | uspto-grants-2006_02 |
| ORD ID | ord-4ff7310d724d4c008e135c9ee2ecac5a |
| Source note | uspto-grants-2006_02 |