Isobutylene → HCID 22244960, compound

HRID 891223Notes

Reaction equation

HRID 891223 reaction equation
[N+:1]([CH:4]([CH3:7])[CH2:5][OH:6])([O-:3])=[O:2].S(=O)(=O)(O)[O-].[Na+].[CH2:14]=[C:15]([CH3:17])[CH3:16]>C1(C)C=CC=CC=1>[C:15]([O:6][CH2:5][CH:4]([N+:1]([O-:3])=[O:2])[CH3:7])([CH3:17])([CH3:16])[CH3:14]

Participants

5

Reactant 3

HCID 8255IsobutyleneHCID 921872-Nitropropan-1-olHCID 516919Sodium Bisulfate

Product 1

HCID 22244960HCID 22244960, compound

Reagents, catalysts & solvents 1

HCID 1140TolueneSolvent2×

Conditions

Temperature
60 °C

Procedure

To a solution of 36.6 g (0.34 mol) of crude 2-nitro-propan-1-ol [prepared according to Example 1a]in 200 ml of toluene in a pressure vessel is added 2 g of sodium bisulfate [NaHSO4]. Through the closed autoclave is added at room temperature 48 g (0.85 mol) of isobutene. The reaction mixture is maintained at 60° C. for 8 hours. The reaction mixture is cooled to room temperature, diluted with toluene and filtered to give a crude solution of 1-tert-butoxy-2-nitro-propane in toluene.

Workup

  1. temperatureThe reaction mixture is cooled to room temperature
  2. filtrationfiltered

Sources & evidence

ORD record
ord-ed9bb76d1c264f518cf3d726ef3e7886
Source dataset
uspto-grants-2006_02
Patent number
US07002010B2

Reaction notes

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