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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 891875Generated: October 30, 2026

3-(Trifluoromethyl)phenylboronic acid → 3-(2-Methyl-imidazol-1-yl-methyl)-5-(3-trifluoromethyl-phenyl)-pyridazine Hydrochloride

https://huagongshe.com/reaction/891875

Reaction equation

Participants

RoleNameHCIDCharge
Reactant3-(Trifluoromethyl)phenylboronic acidHCID 2734388—
Reactant5-Chloro-3-(2-methylimidazol-1-ylmethyl)-pyridazineHCID 11789025—
Product3-(2-Methyl-imidazol-1-yl-methyl)-5-(3-trifluoromethyl-phenyl)-pyridazine HydrochlorideHCID 22240154—

Reaction Steps

The title compound, MS: m/e=319.4 (M+H+), was prepared from 3-trifluoromethylbenzeneboronic acid (commercially available) and 5-chloro-3-(2-methyl-imidazol-1-yl-methyl)-pyridazine.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07005432B2
Source datasetuspto-grants-2006_02
ORD IDord-9462ab83ebd44f918ecd2c85fb29569e
Source noteuspto-grants-2006_02