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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 891896Generated: October 26, 2026

5-Chloro-3-(2-methylimidazol-1-ylmethyl)-pyridazine → 5-(3-Difluoromethyl-phenyl)-3-(2-methyl-imidazol-1-yl-methyl)-pyridazine Hydrochloride

https://huagongshe.com/reaction/891896

Reaction equation

Participants

RoleNameHCIDCharge
Reactant5-Chloro-3-(2-methylimidazol-1-ylmethyl)-pyridazineHCID 11789025—
Reactant2-(3-(Difluoromethyl)phenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolaneHCID 22240167—
Product5-(3-Difluoromethyl-phenyl)-3-(2-methyl-imidazol-1-yl-methyl)-pyridazine HydrochlorideHCID 22240286—

Reaction Steps

The title compound, MS: m/e=301.3 (M+H+), was prepared from 2-(3-difluoromethyl-phenyl)-4,4,5,5-tetramethyl-[1,3,2]dioxaborolane and 5-chloro-3-(2-methyl-imidazol-1-yl-methyl)-pyridazine.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07005432B2
Source datasetuspto-grants-2006_02
ORD IDord-9c5d0845a8984f1a9ccbb5b17f2acc5e
Source noteuspto-grants-2006_02