HuagongsheHuagongshe Chemistry Print Report · For research reference only
5-Chloro-3-(2-methylimidazol-1-ylmethyl)-pyridazine → 5-[3-(1,1-Difluoro-ethyl)-5-fluoro-phenyl]-3-(2-methyl-imidazol-1-yl-methyl)-pyridazine Hydrochloride
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 5-Chloro-3-(2-methylimidazol-1-ylmethyl)-pyridazine | HCID 11789025 | — |
| Reactant | 2-(3-(1,1-Difluoroethyl)-5-fluorophenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane | HCID 22240128 | — |
| Product | 5-[3-(1,1-Difluoro-ethyl)-5-fluoro-phenyl]-3-(2-methyl-imidazol-1-yl-methyl)-pyridazine Hydrochloride | HCID 22240251 | — |
Reaction Steps
The title compound, MS: m/e=333.3 (M+H+), was prepared from 2-[3-(1,1-difluoro-ethyl)-5-fluoro-phenyl]-4,4,5,5-tetramethyl-[1,3,2]dioxaborolane and 5-chloro-3-(2-methyl-imidazol-1-yl-methyl)-pyridazine.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07005432B2 |
| Source dataset | uspto-grants-2006_02 |
| ORD ID | ord-09544736909c455ba5ebb9e997314ee1 |
| Source note | uspto-grants-2006_02 |