HCID 178418806, compound → HCID 178488692, compound

HRID 892030Notes

Reaction equation

HRID 892030 reaction equation
NC1C=CNN=1.O/[CH:8]=[C:9]1\[C:10](=[O:18])[NH:11][C:12]2[C:17]\1=[CH:16][CH:15]=[CH:14][CH:13]=2.[CH3:19][O:20][C:21]1[CH:22]=[C:23]([C:29]2[C:33]([CH3:34])=[N:32][NH:31][C:30]=2[NH2:35])[CH:24]=[CH:25][C:26]=1[O:27][CH3:28]>O1CCCC1>[CH3:19][O:20][C:21]1[CH:22]=[C:23]([C:29]2[C:33]([CH3:34])=[N:32][NH:31][C:30]=2[NH:35][CH:8]=[C:9]2[C:17]3[C:12](=[CH:13][CH:14]=[CH:15][CH:16]=3)[NH:11][C:10]2=[O:18])[CH:24]=[CH:25][C:26]=1[O:27][CH3:28]

Participants

5

Reactant 3

HCID 178418806HCID 178418806, compoundHCID 178488691HCID 178488691, compoundHCID 178517101HCID 178517101, compound

Product 1

HCID 178488692HCID 178488692, compound

Reagents, catalysts & solvents 1

HCID 8028TetrahydrofuranSolvent

Procedure

The named compound is prepared by substituting 4-(3,4-dimethoxy-phenyl)-5-methyl-2H-pyrazol-3-ylamine for 3-aminopyrazole in the reaction of Example 1. Specifically, E & Z-3-[(hydroxy)-methylene]-1,3-dihydro-indol-2-one (0.100 gms.) is reacted with 0.2085 gms. of 4-(3,4-dimethoxy-phenyl)-5-methyl-2H-pyrazol-3-ylamine by refluxing in tetrahydrofuran (2.5 mL).

Workup

  1. customThe named compound is prepared
  2. customin the reaction of Example 1

Sources & evidence

ORD record
ord-e7e4015fcb7f49b38d547d695287da2b
Source dataset
uspto-grants-2006_02
Patent number
US07005444B2

Reaction notes

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