Chlorine → 2-Chloro-6-(chloromethyl)pyridine

HRID 892157Notes

Reaction equation

HRID 892157 reaction equation
ClCl.[Cl:3][C:4]1[N:9]=[C:8]([CH3:10])[CH:7]=[CH:6][CH:5]=1.C1C(=O)N([Cl:18])C(=O)C1>>[Cl:18][CH2:10][C:8]1[CH:7]=[CH:6][CH:5]=[C:4]([Cl:3])[N:9]=1

Participants

4

Reactant 3

HCID 24526ChlorineHCID 31398ChlorosuccinimideHCID 876016-Chloro-2-picoline

Product 1

HCID 155744402-Chloro-6-(chloromethyl)pyridine

Procedure

MS (ESI) 162, 164, 166 (M+H)+, Cl2 pattern. Prepared from 6-chloro-2-picoline and NCS in place of NBS.

Sources & evidence

ORD record
ord-151de93739fe4924b842076d68f556e0
Source dataset
uspto-grants-2006_02
Patent number
US07005440B1

Reaction notes

Loading…