m-Chloroperbenzoic acid → 1-[2-(4-Allyloxy-phenylmethanesulfinyl)-ethyl]-1H-[1,2,3]triazole

Participants

Reaction Steps

To a solution of 1.90 g (6.9 mmol) 1-[2-(4-all yloxy-benzylsulfanyl)-ethyl]-1H-[1,2,3]triazole in 150 ml dichloromethane was added dropwise at −30° C. a solution of 1.86 g (8.3 mmol) 3-chloro-benzenecarboperoxoic acid in 40 ml ethyl acetate and stirring continued for 1 hour. The mixture was allowed to warm up over night, washed with sodium bicarbonate and sodium carbonate solution, then with water, dried and evaporated. Elution form silica with ethyl acetate/methanol 5:1 furnished 1.25 g (62%) 1-[2-(4-allyloxy-phenylmethanesulfinyl)-ethyl]-1H-[1,2,3]triazole as white solid.

Provenance & Evidence