(2-Aminobenzo[d]thiazol-6-yl)methanol → 2-Aminobenzo[d]thiazole-6-carbaldehyde

HRID 892332Notes

Reaction equation

HRID 892332 reaction equation
[NH2:1][C:2]1[S:3][C:4]2[CH:10]=[C:9]([CH2:11][OH:12])[CH:8]=[CH:7][C:5]=2[N:6]=1>C1COCC1.[O-2].[Mn+4].[O-2]>[NH2:1][C:2]1[S:3][C:4]2[CH:10]=[C:9]([CH:11]=[O:12])[CH:8]=[CH:7][C:5]=2[N:6]=1

Participants

4

Reactant 1

HCID 13821540(2-Aminobenzo[d]thiazol-6-yl)methanol

Product 1

HCID 138215412-Aminobenzo[d]thiazole-6-carbaldehyde

Reagents, catalysts & solvents 2

HCID 178418406HCID 178418406, compoundCatalystHCID 8028TetrahydrofuranSolvent

Procedure

110.5 g (0.613 mol) of 1a are stirred in 200 ml of THF with 319.8 g (3.678 mol) of manganese (IV) oxide at room temperature for 3 days. The reaction mixture is filtered, the residue on the filter is washed with THF, and the filtrate is evaporated in vacuo.

Workup

  1. filtrationThe reaction mixture is filtered
  2. washthe residue on the filter is washed with THF
  3. customthe filtrate is evaporated in vacuo

Sources & evidence

ORD record
ord-ca63e8c4dee84989bb31bff71d484377
Source dataset
uspto-grants-1992_06
Patent number
USRE033948

Reaction notes

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