Hydrochloric Acid → 2-(Decylthio)ethanamine

HRID 892395Notes

Reaction equation

HRID 892395 reaction equation
[OH-].[Na+].Cl.Cl.[CH2:5]([S:15][CH2:16][CH2:17][NH2:18])[CH2:6][CH2:7][CH2:8][CH2:9][CH2:10][CH2:11][CH2:12][CH2:13][CH3:14]>>[CH2:5]([S:15][CH2:16][CH2:17][NH2:18])[CH2:6][CH2:7][CH2:8][CH2:9][CH2:10][CH2:11][CH2:12][CH2:13][CH3:14]

Participants

4

Reactant 3

HCID 313Hydrochloric AcidHCID 14798Sodium HydroxideHCID 1511622-(Decylthio)ethanamine hydrochloride

Product 1

HCID 1511612-(Decylthio)ethanamine

Conditions

Temperature
100 °C

Procedure

After the hydrolysis in the above step is complete, the reactor is cooled to about 100° C. and approximately 2.0 equivalents of sodium hydroxide (217 lbs of 50 weight percent solution), based upon the hydrochloric acid added in the production of 2-(decylthio)ethanamine hydrochloride, are introduced with stirring in approximately 30 minutes. The reaction mixture is allowed to settle until phase separation is complete (approximately 30 minutes) and the 2-(decylthio)ethanamine is decanted off. The 2-(decylthio)ethanamine can be passed over a drying agent such as sodium sulfate, or may be vacuum stripped to remove any dissolved and/or entrained water.

Workup

  1. customAfter the hydrolysis in the above step
  2. additionare introduced
  3. customto settle until phase separation
  4. custom(approximately 30 minutes)
  5. customthe 2-(decylthio)ethanamine is decanted off
  6. customto remove
  7. dissolutionany dissolved

Sources & evidence

ORD record
ord-3cc373e3cff14e8abe4f9257fe10206d
Source dataset
uspto-grants-1992_06
Patent number
US05118534

Reaction notes

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