Propylamine → HCID 135537129, compound

Participants

Reaction Steps

4-Chloro-6-hydroxy-2-(2-propoxyphenyl)pyrimidine (0.66 g), n-propylamine (1.8 g) and ethanol (20 ml) was heated at 90° C. in a pressure vessel for 16 hours. The cooled reaction mixture was evaporated under reduced pressure to lo yield an oil which solidified on washing with water. The residue was recrystallised from isopropanol: water to yield the title compound, 0.56 g, m.p. 172°-3° C.

Provenance & Evidence