Potassium Carbonate → HCID 19001225, compound

HRID 892695Notes

Reaction equation

HRID 892695 reaction equation
[OH:1][C:2]1[CH:19]=[CH:18][C:5]([O:6][C:7]2[CH:16]=[N:15][C:14]3[C:9](=[CH:10][CH:11]=[C:12]([Cl:17])[CH:13]=3)[N:8]=2)=[CH:4][CH:3]=1.Br[CH:21]([CH3:31])[C:22]([O:24][CH2:25][C:26]1[S:27][CH:28]=[CH:29][CH:30]=1)=[O:23].C(=O)([O-])[O-].[K+].[K+]>C(#N)C>[Cl:17][C:12]1[CH:13]=[C:14]2[C:9](=[CH:10][CH:11]=1)[N:8]=[C:7]([O:6][C:5]1[CH:18]=[CH:19][C:2]([O:1][CH:21]([CH3:31])[C:22]([O:24][CH2:25][C:26]3[S:27][CH:28]=[CH:29][CH:30]=3)=[O:23])=[CH:3][CH:4]=1)[CH:16]=[N:15]2

Participants

5

Reactant 3

HCID 11430Potassium CarbonateHCID 109894084-[(6-Chloroquinoxalin-2-yl)oxy]phenolHCID 19001234HCID 19001234, compound

Product 1

HCID 19001225HCID 19001225, compound

Reagents, catalysts & solvents 1

HCID 6342AcetonitrileSolvent

Procedure

To a 250 milliliter roundbottom flask equipped with stir bar, reflux condenser, connecting tube, and nitrogen atmosphere were added 4.3781 grams (0.0161 moles) of 2-(4-hydroxyphenoxy)-6-chloroquinoxaline, 4.000 grams (0.0161 moles) of 2-thiophenylmethyl 2-bromopropanoate, 4.4377 grams (0.0321 moles) of anhydrous potassium carbonate, and 100 milliters of acetonitrile.

Workup

  1. customTo a 250 milliliter roundbottom flask equipped
  2. temperaturereflux condenser

Sources & evidence

ORD record
ord-6b2116138d9d40c6b98d85fd432b507a
Source dataset
uspto-grants-1992_06
Patent number
US05120348

Reaction notes

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