Diethyl Ether → HCID 19894296, compound

HRID 892844Notes

Reaction equation

HRID 892844 reaction equation
[C:1]([C:4]1[CH:9]=[C:8]([O:10][C:11]2[CH:16]=[CH:15][CH:14]=[CH:13][CH:12]=2)[CH:7]=[CH:6][C:5]=1[OH:17])(=[O:3])[CH3:2].C(=O)([O-])[O-].[Cs+].[Cs+].[CH2:24](Br)[CH:25]=[CH2:26].CCOCC>CN(C=O)C>[C:1]([C:4]1[CH:9]=[C:8]([O:10][C:11]2[CH:12]=[CH:13][CH:14]=[CH:15][CH:16]=2)[CH:7]=[CH:6][C:5]=1[O:17][CH2:26][CH:25]=[CH2:24])(=[O:3])[CH3:2]

Participants

6

Reactant 4

HCID 3283Diethyl EtherHCID 7841Allyl bromideHCID 10796Cesium carbonateHCID 12264993HCID 12264993, compound

Product 1

HCID 19894296HCID 19894296, compound

Reagents, catalysts & solvents 1

HCID 6228DimethylformamideSolvent

Procedure

2-Acetyl-4-phenoxyphenol (4.22 g, 18.5 mmol) and cesium carbonate (15.0 g, 46.0 mmol) are taken in DMF (50 mL) and treated with allyl bromide (2.24 g, 18.5 mmol). The mixture is stirred overnight at room temperature. Ether is added and the mixture is washed with saturated aqueous ammonium chloride solution. The organic phase is dried over magnesium sulfate and evaporated to give 2-acetyl-1-allyloxy-4-phenoxybenzene as a yellow solid.

Workup

  1. washthe mixture is washed with saturated aqueous ammonium chloride solution
  2. dry with materialThe organic phase is dried over magnesium sulfate
  3. customevaporated

Sources & evidence

ORD record
ord-d38515df178745459d9445fca5f7d13c
Source dataset
uspto-grants-1992_06
Patent number
US05120758

Reaction notes

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