Hydrochloric Acid → 6-ethyl-3-[2-(isopropoxyimino)-2-(4-methoxyphenyl)ethyl]-1-{[2'-(5-oxo-4,5-dihydro-1,2,4-oxadiazol-3-yl)biphenyl-4-yl]methyl}thieno[2,3-d]pyrimidine-2,4(1H,3H)-dione

HRID 89292Notes

Reaction equation

HRID 89292 reaction equation
[CH2:1]([CH3:2])[c:3]1[cH:4][c:5]2[c:6]([n:7]([CH2:24][c:25]3[cH:26][cH:27][c:28](-[c:31]4[c:32](-[c:37]5[n:38][o:39][c:40](=[O:42])[nH:41]5)[cH:33][cH:34][cH:35][cH:36]4)[cH:29][cH:30]3)[c:8](=[O:23])[n:9]([CH2:12][C:13](=[O:14])[c:15]3[cH:16][cH:17][c:18]([O:21][CH3:22])[cH:19][cH:20]3)[c:10]2=[O:11])[s:43]1.[CH3:62][CH2:63][OH:64].[CH:58]([Cl:59])([Cl:60])[Cl:61].[ClH:44].[ClH:56].[NH2:45][O:46][CH:47]([CH3:48])[CH3:49].[OH2:57].[cH:50]1[cH:51][cH:52][n:53][cH:54][cH:55]1>>[CH2:1]([CH3:2])[c:3]1[cH:4][c:5]2[c:6]([n:7]([CH2:24][c:25]3[cH:26][cH:27][c:28](-[c:31]4[c:32](-[c:37]5[n:38][o:39][c:40](=[O:42])[nH:41]5)[cH:33][cH:34][cH:35][cH:36]4)[cH:29][cH:30]3)[c:8](=[O:23])[n:9]([CH2:12][C:13]([c:15]3[cH:16][cH:17][c:18]([O:21][CH3:22])[cH:19][cH:20]3)=[N:45][O:46][CH:47]([CH3:48])[CH3:49])[c:10]2=[O:11])[s:43]1

Participants

8

Reactant 7

HCID 313Hydrochloric Acid2×HCID 702EthanolHCID 962WaterHCID 1049PyridineHCID 6212ChloroformHCID 2768923Hydroxylamine, O-(1-methylethyl)-HCID 1358760656-ethyl-3-[2-(4-methoxyphenyl)-2-oxoethyl]-1-{[2'-(5-oxo-4,5-dihydro-1,2,4-oxadiazol-3-yl)biphenyl-4-yl]methyl}thieno[2,3-d]pyrimidine-2,4(1H,3H)-dione

Product 1

HCID 1360523576-ethyl-3-[2-(isopropoxyimino)-2-(4-methoxyphenyl)ethyl]-1-{[2'-(5-oxo-4,5-dihydro-1,2,4-oxadiazol-3-yl)biphenyl-4-yl]methyl}thieno[2,3-d]pyrimidine-2,4(1H,3H)-dione

Sources & evidence

ORD record
ord-f992e79614ed4e81836297c94054f870
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (2/10)

Reaction notes

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