Sodium Iodide → 1-Iodoethyl cyclohexyl carbonate

HRID 892921Notes

Reaction equation

HRID 892921 reaction equation
[C:1](=[O:13])([O:6][CH:7]1[CH2:12][CH2:11][CH2:10][CH2:9][CH2:8]1)[O:2][CH:3](Cl)[CH3:4].[I-:14].[Na+]>C(#N)C>[C:1](=[O:13])([O:6][CH:7]1[CH2:12][CH2:11][CH2:10][CH2:9][CH2:8]1)[O:2][CH:3]([I:14])[CH3:4]

Participants

4

Reactant 2

HCID 5238Sodium IodideHCID 112295291-Chloroethyl Cyclohexyl Carbonate

Product 1

HCID 111092781-Iodoethyl cyclohexyl carbonate

Reagents, catalysts & solvents 1

HCID 6342AcetonitrileSolvent

Procedure

A solution of 1.65 g of 1-chloroethyl cyclohexyl carbonate and 5.0 g of sodium iodide in 50 ml of acetonitrile is stirred at 70° C. for 45 minutes and then concentrated under reduced pressure. The residue is extracted with ether. The extracts are combined and evaporated under reduced pressure to remove the solvent to give the title compound as pale yellow oil.

Workup

  1. concentrationconcentrated under reduced pressure
  2. extractionThe residue is extracted with ether
  3. customevaporated under reduced pressure
  4. customto remove the solvent

Sources & evidence

ORD record
ord-874f7ee1cfc74885845d530405c47dee
Source dataset
uspto-grants-1992_06
Patent number
US05120841

Reaction notes

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