HuagongsheHuagongshe Chemistry Print Report · For research reference only
HCID 19748502, compound → 2-(1-AMINOETHYL)PHENOL HYDROCHLORIDE
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | HCID 19748502 | HCID 19748502 | — |
| Catalyst | Palladium | HCID 23938 | — |
| Solvent | Methanol | HCID 887 | — |
| Product | 2-(1-AMINOETHYL)PHENOL HYDROCHLORIDE | HCID 19748524 | 102.4% |
Reaction Steps
A mixture obtained by adding 2.64 g of (+)-1-(2-benzyloxyphenyl)ethylamine hydrochloride prepared in Referential Example (3-1) and 0.26 g of 5% Pd-C to 40 ml of methanol was subjected to hydrogenation at room temperature and normal pressure, whereby 256 ml of hydrogen was absorbed. After filtering off the catalyst, the filtrate was concentrated under reduced pressure to give 1.78 g of (+)-1-(2-hydroxyphenyl)ethylamine hydrochloride.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05120853 |
| Source dataset | uspto-grants-1992_06 |
| ORD ID | ord-4b107e0caab545a3820dcee34921607a |
| Source note | uspto-grants-1992_06 |