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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 892936Generated: October 30, 2026

HCID 19748502, compound → 2-(1-AMINOETHYL)PHENOL HYDROCHLORIDE

https://huagongshe.com/reaction/892936

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHCID 19748502HCID 19748502—
CatalystPalladiumHCID 23938—
SolventMethanolHCID 887—
Product2-(1-AMINOETHYL)PHENOL HYDROCHLORIDEHCID 19748524102.4%

Reaction Steps

A mixture obtained by adding 2.64 g of (+)-1-(2-benzyloxyphenyl)ethylamine hydrochloride prepared in Referential Example (3-1) and 0.26 g of 5% Pd-C to 40 ml of methanol was subjected to hydrogenation at room temperature and normal pressure, whereby 256 ml of hydrogen was absorbed. After filtering off the catalyst, the filtrate was concentrated under reduced pressure to give 1.78 g of (+)-1-(2-hydroxyphenyl)ethylamine hydrochloride.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS05120853
Source datasetuspto-grants-1992_06
ORD IDord-4b107e0caab545a3820dcee34921607a
Source noteuspto-grants-1992_06