Pyridine → 1-O-tert-butyl 2-O-ethyl 4-(4-methylphenyl)sulfonyloxypyrrolidine-1,2-dicarboxylate

HRID 89297Notes

Reaction equation

HRID 89297 reaction equation
[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6](=[O:7])[N:8]1[CH:9]([C:14](=[O:15])[O:16][CH2:17][CH3:18])[CH2:10][CH:11]([OH:13])[CH2:12]1.[c:19]1([CH3:29])[cH:20][cH:21][c:22]([S:25](=[O:26])(=[O:27])[Cl:28])[cH:23][cH:24]1.[cH:30]1[cH:31][cH:32][n:33][cH:34][cH:35]1>>[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6](=[O:7])[N:8]1[CH:9]([C:14](=[O:15])[O:16][CH2:17][CH3:18])[CH2:10][CH:11]([O:13][S:25]([c:22]2[cH:21][cH:20][c:19]([CH3:29])[cH:24][cH:23]2)(=[O:26])=[O:27])[CH2:12]1

Participants

4

Reactant 3

HCID 1049PyridineHCID 73974-Toluenesulfonyl chlorideHCID 12709312O1-tert-butyl O2-ethyl 4-hydroxypyrrolidine-1,2-dicarboxylate

Product 1

HCID 133846051-O-tert-butyl 2-O-ethyl 4-(4-methylphenyl)sulfonyloxypyrrolidine-1,2-dicarboxylate

Sources & evidence

ORD record
ord-debc7994a8c94d3b9db267ad4fc5700e
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (2/10)

Reaction notes

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