HuagongsheHuagongshe Chemistry Print Report · For research reference only
Triethylamine → 1,2-Methylenedioxy-4-[3-mesyloxypropyl]benzene
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Triethylamine | HCID 8471 | — |
| Reactant | Methanesulfonyl chloride | HCID 31297 | — |
| Reactant | 1,3-Benzodioxole-5-propanol | HCID 11030414 | — |
| Solvent | Dichloromethane | HCID 6344 | — |
| Product | 1,2-Methylenedioxy-4-[3-mesyloxypropyl]benzene | HCID 19894628 | — |
Reaction Steps
A solution of 1,2-methylenedioxy-4-[3-hydorxypropyl]benzene, (10.0 g), methanesulfonyl chloride (6.33 g, 4.28 ml) and triethylamine (5.6 g) in methylene chloride (100 ml) is stirred at 0° for 2 hr. The reaction mixture is partitioned between methylene chloride and aqueous sodium bicarbonate. The organic phase is dried over sodium sulfate and concentrated. The residue is dissolved in acetonitrile (100 ml).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05120843 |
| Source dataset | uspto-grants-1992_06 |
| ORD ID | ord-bdb99ad8f8a647e890dbbb52ce84a834 |
| Source note | uspto-grants-1992_06 |