反应详情

A solution of 1,2-methylenedioxy-4-[3-hydorxypropyl]benzene, (10.0 g), methanesulfonyl chloride (6.33 g, 4.28 ml) and triethylamine (5.6 g) in methylene chloride (100 ml) is stirred at 0° for 2 hr. The reaction mixture is partitioned between methylene chloride and aqueous sodium bicarbonate. The organic phase is dried over sodium sulfate and concentrated. The residue is dissolved in acetonitrile (100 ml).

1. customThe reaction mixture is partitioned between methylene chloride and aqueous sodium bicarbonate
2. dry with materialThe organic phase is dried over sodium sulfate
3. concentrationconcentrated
4. dissolutionThe residue is dissolved in acetonitrile (100 ml)