HuagongsheHuagongshe Chemistry Print Report · For research reference only
Glycine → HCID 131717430, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Glycine | HCID 750 | — |
| Reactant | Dicyclohexylcarbodiimide | HCID 10868 | — |
| Reactant | Glycine ethyl ester | HCID 12176 | — |
| Reactant | N-(2-Pyridyl)glycine | HCID 193885 | — |
| Reactant | N-Pyridin-2-ylglycine--hydrogen chloride (1/1) | HCID 14238451 | — |
| Solvent | Dichloromethane | HCID 6344 | — |
| Product | HCID 131717430 | HCID 131717430 | — |
Reaction Steps
The synthesis of peptide bond reaction from the 2-pyridylglycine.hydrochloride and glycine can be carried out, for example, as follows: To N-2-pyridylglycine, are added dichloromethane, N,N'-dicyclohexylcarbodiimide and glycine ethyl ester. After stirring at room temperature for several hours, the reaction solution is filtered. The filtrate is purified by using, for example, high performance liquid chromatography to give Pyr-Gly-Gly-OEt.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05120644 |
| Source dataset | uspto-grants-1992_06 |
| ORD ID | ord-d83689969c604495b735948d06870adc |
| Source note | uspto-grants-1992_06 |