Hydrogen Peroxide → HCID 178511810, compound

HRID 893063Notes

Reaction equation

HRID 893063 reaction equation
[NH2:1][C@H:2]([C:9]([OH:11])=[O:10])[CH2:3][C:4]1[N:8]=[CH:7][NH:6][CH:5]=1.[OH:12][OH:13]>O>[NH2:1][C@H:2]([C:9]([OH:11])=[O:10])[CH2:3][C:4]1[N:8]=[CH:7][NH:6][CH:5]=1.[OH:12][OH:13]

Participants

4

Reactant 2

HCID 784Hydrogen PeroxideHCID 178419078HCID 178419078, compound

Product 1

HCID 178511810HCID 178511810, compoundYield 82%

Reagents, catalysts & solvents 1

HCID 962WaterSolvent

Procedure

21 g of histidine and 189 g of water were placed in a 300 ml conical beaker. To the resultant slurry was added 11.5 g of 60% aqueous hydrogen peroxide little by little under stirring. After 20 minutes of stirring, the slurry was filtered off and the resultant crystals were washed with cold methanol, then dried to afford 2.08 g (82%) of a histidine-hydrogen peroxide adduct. The decomposition temperature of the adduct was found to be 146.8° C.

Workup

  1. stirringAfter 20 minutes of stirring
  2. filtrationthe slurry was filtered off
  3. washthe resultant crystals were washed with cold methanol
  4. customdried

Sources & evidence

ORD record
ord-930efc98286d42b3b7a15c47c4c873d7
Source dataset
uspto-grants-1992_06
Patent number
US05122354

Reaction notes

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