Triethylamine → HCID 19096832, compound

HRID 893197Notes

Reaction equation

HRID 893197 reaction equation
Cl[C:2]([CH:4]([CH2:10][CH3:11])[C:5]([O:7][CH2:8][CH3:9])=[O:6])=[O:3].[Br:12][C:13]1[CH:19]=[CH:18][C:16]([NH2:17])=[C:15]([CH3:20])[CH:14]=1.C(N(CC)CC)C>>[Br:12][C:13]1[CH:19]=[CH:18][C:16]([NH:17][C:2]([CH:4]([CH2:10][CH3:11])[C:5]([O:7][CH2:8][CH3:9])=[O:6])=[O:3])=[C:15]([CH3:20])[CH:14]=1

Participants

4

Reactant 3

HCID 8471TriethylamineHCID 114234-Bromo-2-methylanilineHCID 12440797HCID 12440797, compound

Product 1

HCID 19096832HCID 19096832, compoundYield 66.7%

Procedure

Ethyl 2-(chlorocarbonyl)butanoate (5.8 grams, 0.03 mole), 4-bromo-2-methylaniline (5.0 grams, 0.03 mole) and triethylamine (3.27 grams, 0.03 mole) were reacted under conditions similar to that described for Example I to give 7.4 grams (0.02 mole) of ethyl 2-(4-bromo-2-methylphenylaminocarbonyl)butanoate as a white solid having a melting point of 98° C.-100° C.

Sources & evidence

ORD record
ord-c99e4370d2bd43fcb9eb2ef4027cc861
Source dataset
uspto-grants-1992_06
Patent number
US05123951

Reaction notes

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