Cyclopropylboronic acid → 5-[1-(4-Cyclopropyl-2-trifluoromethyl-benzyl)-1H-indazol-5-ylmethylene]-2-(4-methyl-piperazin-1-yl)-thiazol-4-one
Reaction equation
[Br:1][c:2]1[cH:3][c:4]([C:32]([F:33])([F:34])[F:35])[c:5]([CH2:6][n:7]2[n:8][cH:9][c:10]3[cH:11][c:12]([CH:16]=[C:17]4[C:18](=[O:29])[N:19]=[C:20]([N:22]5[CH2:23][CH2:24][N:25]([CH3:28])[CH2:26][CH2:27]5)[S:21]4)[cH:13][cH:14][c:15]23)[cH:30][cH:31]1.[CH:36]1([B:39]([OH:40])[OH:41])[CH2:37][CH2:38]1>>[c:2]1([CH:36]2[CH2:37][CH2:38]2)[cH:3][c:4]([C:32]([F:33])([F:34])[F:35])[c:5]([CH2:6][n:7]2[n:8][cH:9][c:10]3[cH:11][c:12]([CH:16]=[C:17]4[C:18](=[O:29])[N:19]=[C:20]([N:22]5[CH2:23][CH2:24][N:25]([CH3:28])[CH2:26][CH2:27]5)[S:21]4)[cH:13][cH:14][c:15]23)[cH:30][cH:31]1Participants
3
Reactant 2
Product 1
Sources & evidence
- ORD record
- ord-d79b10ff667a43fa991e3462fcc670e7
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (2/10)
Reaction notes
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